Director Clinical Research-Cardiology

Alnylam Pharmaceuticals Inc

Cambridge, MAFull-time

242K–328K a year

Behavioral Health Market Context

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Benefits

U.S. Pay Range: $242,300.00 - $327,900.00The pay range reflects the full-time base salary range we expect to pay for this role at the time of postingBase pay will be determined based on a number of factors, including but not limited to relevant experience, skills, and educationThis role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity)Alnylams robust Total Rewards package is designed to support your overall health and well-beingWe offer comprehensive benefits, including:Medical, dental, and vision coverageLife and disability insuranceA lifestyle reimbursement programFlexible spending and health savings accountsA 401(k) with a generous company matchEligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaksWe also offer generous family resources and leave

Job Description

Be the strategic leader providing a strong, clear voice for the clinical program. Develop creative but realistic approaches to drug development and lead clinical efforts to secure global regulatory approvals.

Oversight of trial conduct and safety
Provide strategic consultation and guidance to Research on all decisions that have significant clinical components and implications.

Collaborate closely with Preclinical Regulatory Affairs and Medical Affairs to ensure tight strategic integration of product development plans.

Be accountable via Clinical Research and Operations for all relevant timelines and deliverables. Supervise closely all major written deliverables, regulatory submissions, original articles, abstracts, and presentation materials.

Be responsible for final review and sign off with respect to all controlled documents, including protocols, investigator brochures, and informed consent forms.

Influence internal and external audiences in a high-impact, highly visible fashion.

A highly driven, dynamic, engaged, and accomplished physician-scientist with experience and insight will thrive in this role.

MD with strong research background or MD/PhD with best-of-class clinical and/or research training, as shown through research support and peer-reviewed publications.

Board Certification or equivalent or specialist training in cardiology or metabolic disease is desirable.

3 years industry experience or equivalent clinical-academic experience.

Sound scientific and clinical judgment
Familiarity with concepts of clinical research and clinical trial design, including biostatistics and regulatory agency organization guidelines and practices.

Ability to effectively present ideas and document complex medical/clinical concepts in both written and oral communication.

History of solving problems while exhibiting superior judgment and a balanced, realistic understanding of issues.

Outstanding leadership and collaboration skills working within a matrix environment.

Experience and knowledge of working with biotech/pharma partners.

Thrive in a highly entrepreneurial biotech environment and embrace Alnylams culture of science, passion, and urgency.

U.S. Pay Range: $242,300.00 - $327,900.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors, including but not limited to relevant experience, skills, and education.

This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylams robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits, including:
• Medical, dental, and vision coverage
• Life and disability insurance
• A lifestyle reimbursement program
• Flexible spending and health savings accounts
• A 401(k) with a generous company match

Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks.

We also offer generous family resources and leave.

Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

Skills:
Biostatistics, Biotech and Pharmaceutical, Brochures, Cardiology, Clinical Research, Clinical Trial, Document Management, Drug Development, Entrepreneurship, Informed Consent, Leadership, Medical Affairs, Metabolic Disorders, Operations Research, Presentation/Verbal Skills, Problem Solving Skills, Product Development, Publications, Regulations, Regulatory Submissions, Reimbursement, Team Player

About the Company:
Alnylam Pharmaceuticals Inc

Alnylam is leading the translation of RNAi as a new class of innovative medicines, with a core focus on RNAi therapeutics toward genetically defined targets for the treatment of serious, life-threatening diseases with limited treatment options for patients and their caregivers.

Industry:
Healthcare Services

Founded:
2002

Website:
http://www.alnylam.com/

Qualifications

  • MD with strong research background or MD/PhD with best-of-class clinical and/or research training, as shown through research support and peer-reviewed publications
  • 3 years industry experience or equivalent clinical-academic experience
  • Ability to effectively present ideas and document complex medical/clinical concepts in both written and oral communication
  • History of solving problems while exhibiting superior judgment and a balanced, realistic understanding of issues
  • Outstanding leadership and collaboration skills working within a matrix environment
  • Experience and knowledge of working with biotech/pharma partners
  • Thrive in a highly entrepreneurial biotech environment and embrace Alnylams culture of science, passion, and urgency
  • Biostatistics, Biotech and Pharmaceutical, Brochures, Cardiology, Clinical Research, Clinical Trial, Document Management, Drug Development, Entrepreneurship, Informed Consent, Leadership, Medical Affairs, Metabolic Disorders, Operations Research, Presentation/Verbal Skills, Problem Solving Skills, Product Development, Publications, Regulations, Regulatory Submissions, Reimbursement, Team Player

Responsibilities

  • Be the strategic leader providing a strong, clear voice for the clinical program
  • Develop creative but realistic approaches to drug development and lead clinical efforts to secure global regulatory approvals
  • Oversight of trial conduct and safety
  • Provide strategic consultation and guidance to Research on all decisions that have significant clinical components and implications
  • Collaborate closely with Preclinical Regulatory Affairs and Medical Affairs to ensure tight strategic integration of product development plans
  • Be accountable via Clinical Research and Operations for all relevant timelines and deliverables
  • Supervise closely all major written deliverables, regulatory submissions, original articles, abstracts, and presentation materials
  • Be responsible for final review and sign off with respect to all controlled documents, including protocols, investigator brochures, and informed consent forms
  • Influence internal and external audiences in a high-impact, highly visible fashion
  • A highly driven, dynamic, engaged, and accomplished physician-scientist with experience and insight will thrive in this role
  • Familiarity with concepts of clinical research and clinical trial design, including biostatistics and regulatory agency organization guidelines and practices


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