Clinical Trial Leader

Tango Therapeutics

Hoboken, NJFull-timePosted May 6, 2026

Behavioral Health Market Context

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Qualifications

  • 8+ years of trial management experience with 3+ years in trial leadership position
  • Bachelor's degree in Life Sciences, Pharmacy or related field (required)
  • Experience working in global clinical development organization
  • Direct experience with health authority inspections (FDA, EMA, MHRA, etc.) incl
  • 1 more items(s)

Responsibilities

  • We are seeking a Clinical Trial Leader (CTL) to lead cross-functional clinical trial teams (CTTs) in the execution of clinical trials of Tango's portfolio
  • This role will chair the CTT and represent the cross-functional team to internal governance bodies
  • The CTL will be an internal escalation point for other CTT members
  • In a fast-paced, small biotech environment, the CTL will operationally lead the set-up, conduct and reporting of clinical trials as per approved timelines, budget, regulatory requirements, and internal standards
  • This individual will play a key role in the execution and delivery of clinical trial objectives
  • The ideal candidate is highly collaborative, detail-oriented, and comfortable operating in a hands-on environment, with a focus on building scalable processes, tools, and best practices to support efficient and compliant clinical trial execution
  • Lead cross-functional Clinical Trial Team (CTT) in the planning, execution, and reporting of outsourced clinical trial
  • Provide regular updates to internal governance bodies
  • Serve as the primary liaison between the sponsor and CRO to ensure alignment of trial objectives, timelines, and deliverables
  • Oversee CRO performance, ensuring adherence to scope, budget, and timelines
  • Contribute to protocol development and review of key study documents (e.g., ICFs, CRFs, monitoring plans)
  • Lead the development of trial-specific plans including risk management, communication, and oversight plans
  • Support site selection and feasibility assessments in collaboration with CRO and internal stakeholders
  • Monitor trial progress through metrics and KPIs
  • In collaboration with Operational Excellence and Compliance, define an optimal RBQM framework to efficiently control quality throughout the trial
  • Proactively identify risks and issues and support the development and implementation of mitigation strategies and action plans
  • Ensure timely delivery of trial milestones including patient recruitment, data collection, and interim analyses
  • Manage trial budgets, change orders, and invoice reconciliation in collaboration with vendor management and finance
  • Ensure study conduct in compliance with ICH GCP, ISO standards, regulatory requirements, and internal standards
  • Participate in audits and inspections
  • Ensure timely resolution of findings
  • Review and approve essential documents and study deliverables
  • Oversee database lock, clinical study report (CSR) development, and study close-out activities
  • Contribute to regulatory submissions and responses as needed
  • 21 more items(s)


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