Principal Medicinal Chemist

VirtualVocations

Oceanside, CAFull-timePosted Apr 7, 2026

Behavioral Health Market Context

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Job Description

Design novel compounds using structure-based and ligand-based approaches to optimize potency, selectivity, and drug-like properties

Required Qualifications

PhD in Organic Chemistry or related field with 3-8 years of industry experience (or MS with 5-10 years, BS with 8-15 years) in medicinal chemistry

Proven track record of advancing drug discovery programs through key milestones

Deep expertise in synthetic organic chemistry and drug design methodologies

Experience managing external CROs and collaborating across disciplines

Experience integrating computational chemistry or AI-driven design into medicinal chemistry workflows is a plus

Qualifications

  • PhD in Organic Chemistry or related field with 3-8 years of industry experience (or MS with 5-10 years, BS with 8-15 years) in medicinal chemistry
  • Proven track record of advancing drug discovery programs through key milestones
  • Deep expertise in synthetic organic chemistry and drug design methodologies
  • Experience managing external CROs and collaborating across disciplines

Benefits

    Responsibilities

    • Propose and independently drive medicinal chemistry strategies from hit identification through lead optimization to development candidate selection
    • Lead chemistry efforts within cross-functional project teams, including computational scientists and biologists
    • Design novel compounds using structure-based and ligand-based approaches to optimize potency, selectivity, and drug-like properties


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